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Olofsson LE, Pierce AA, Xu AW. Functional requirement of AgRP and NPY neurons in ovarian cycle-dependent regulation of food intake. Proceedings of the National Academy of Science, USA. Published online before print September 2, 2009, doi: 10.1073/pnas.0904747106. Piper ML, Unger EK, Myers MG Jr., Xu AW. Specific physiologic roles for Stat3 in leptin receptor-expressing neurons. Mol Endocrinol. 2008, 22(3): 751-9. Claret M, Smith MA, Batterham RL, Selman C, Choudhury AI, Fryer LG, Clements M, Al-Qassab H, Heffron H, Xu AW, Speakman JR, Barsh GS, Viollet B, Vaulont S, Ashford ML, Carling D, Withers DJ. AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. J. Clin. Invest. 2007, 117(8): 2325-36. Xu AW, Ste-Marie L, Kaelin CB, Barsh GS. Inactivation of signal transducer and activator of transcription 3 in Proopiomelanocortin (Pomc) neurons causes decreased Pomc expression, mild obesity and defects in compensatory refeeding. Endocrinology. 2007, 148(1): 72-80. Kitamura T, Feng Y, Kitamura IY, Chua SC, Xu AW, Barsh GS, Rossetti L, Accili D. Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake. Nat Med. 2006, 12(5): 534-40. Kaelin CB, Gong L, Xu AW, Yao F, Hockman K, Morton GJ, Schwartz MW, Barsh GS, MacKenzie RG. Stat binding sites but not Stat3 are required for fasting-induced transcription of Agouti-related protein mRNA. Mol. Endocrinol. 2006, 20(10): 2591-602. Xu AW, Barsh GS. MC4R neurons weigh in differently. Nat Neurosci. 2006, 9(1): 15-6. Xu AW, Kaelin CB, Morton G, Ogimoto K, Stanhope K, Graham J, Baskin DG, Havel P, Schwartz MW, Barsh GS. Effects of hypothalamic neurodegeneration on energy balance. PloS Biology. 2005. 3(12): e415 Gropp E, Shanabrough M, Borok E, Xu AW, Janoschek R, Buch T, Plum L, Balthasar N, Hampel B, Waisman A, Barsh GS, Horvath TL, Bruning JC. Agouti-related peptide-expressing neurons are mandatory for feeding. Nat Neurosci. 2005, 8(10): 1289-91 Xu AW, Kaelin CB, Takeda K, Akira S, Schwartz MW, Barsh GS. PI3K integrates the action of insulin and leptin on hypothalamic neurons. J. Clin. Invest. 2005, 115(4): 951-8. Choudhury AI, Heffron H, Smith MA, Al-Qassab H, Xu AW, Selman C, Simmgen M, Clements M, Claret M, Maccol G, Hisadome K, Diakonov I, Moosajee V, Bell JD, Speakman JR, Batterham RL, Barsh GS, Ashford MLJ, Withers DJ. The role of insulin receptor substrate 2 in hypothalamic and beta cell function. J. Clin. Invest. 2005, 115(4): 940-50. Kaelin CB, Xu AW, Lu XY, Barsh GS. Transcriptional regulation of Agouti-related protein (Agrp) in transgenic mice. Endocrinology. 2004, 145(12): 5798-806. |
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