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JOURNAL CLUB ARCHIVE
12/16/13 Kosaku Shinoda Direct Proteomic Quantification of the Secretome of Activated Immune Cells
12/9/13 Bill Krause An Integrated Serotonin and Octopamine Neuronal Circuit Directs the Release of an Endocrine Signal to Control C. elegans Body Fat
12/2/13 Martin Valdearcos Contreras Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance
11/18/13 Ernie Yulyaningsih Evidence for NG2-glia Derived, Adult-Born Functional Neurons in the Hypothalamus
10/21/13 Shi-Bing Yang Dendritic Peptide Release Mediates Interpopulation Crosstalk between Neurosecretory and Preautonomic Networks
10/14/13 Dylan Lowe MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity
10/1/13 (*Tuesday*) MetaboRIPS Jose Heredia (Chawla Lab) and Stuart Smith (German Lab) in Gladstone Conf Rm C&D at 4 pm (note special day of the week)
9/23/13 Jess Porter Abate Identification of an Adipogenic Niche for Adipose Tissue Remodeling and Restoration
9/16/13 Linet Mera Tracking adipogenesis during white adipose tissue development, expansion and regeneration
9/9/13 Jillian Varonin Leptin Engages a Hypothalamic Neurocircuitry to Permit Survival in the Absence of Insulin
8/26/13 Megan Robblee Adipocyte Lipid Chaperone aP2 Is a Secreted Adipokine Regulating Hepatic Glucose Production
8/19/13 James Warne Melanocortin 4 Receptors Reciprocally Regulate Sympathetic and Parasympathetic Preganglionic Neurons
8/12/13 Allison Xu Neonatal leptin exposure specifies innervation of presympathetic hypothalamic neurons and improves the metabolic status of leptin-deficient mice
**8/7/13** Ivan Rudenko Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH
7/22/13 Suneil Koliwad Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation
7/15/13 Yi Wang Rare variants in single-minded 1 (SIM1) are associated with severe obesity
7/8/13 Stephanie Van Veen A guide to analysis of mouse energy metabolism
7/1/13 Kosaku Shinoda Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation
6/24/13 MetaboRIPS MetaboRIPS: Xin Chen Lab and Miyuki Suzawa (Ingraham Lab) (Gladstone Rm C&D)
6/17/13 Paula Jossan Angiotensin-converting enzyme inhibition reduces food intake and weight gain and improves glucose tolerance in melanocortin-4 receptor deficient female rats
6/10/13 Martin Valdearcos Contreras Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice
6/3/13 Linet Mera EBF2 Determines and Maintains Brown Adipocyte Identity
5/20/13

Bill Krause

Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively
5/13/13 Shi-Bing Yang Neurotransmitter Switching in the Adult Brain Regulates Behavior
5/6/13 Si Sonne Bi-directional interconversion of brite and white adipocytes
4/29/13 No JC Diabetes Center Retreat
4/22/13 MetaboRIPS MetaboRIPS: Masako Asahina (Ashrafi Lab) and Ari Molofsky (Locksley Lab) (CVRI SC159)
4/15/13 Ernie Yulyaningsih Fgf10-Expressing Tanycytes Add New Neurons to the Appetite/Energy-Balance Regulating Centers of the Postnatal and Adult Hypothalamus
4/8/13 Allison Xu Leptin regulates glutamate and glucose transporters in hypothalamic astrocytes
4/1/13 Jess Porter Abate Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity
3/25/13 MetaboRIPS MetaboRIPS: Kosaku Shinoda (Kajimura Lab) (Gladstone Rm.C&D)
3/11/13 Jillian Varonin Inhibition of Leptin Regulation of Parasympathetic Signaling as a Cause of Extreme Body Weight-Associated Asthma
3/4/13 Kana Ohyama TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis
2/25/13 MetaboRIPS MetaboRIPS: Camella Wilson (E Weiss Lab) and Aras Mattis (Willenbring Lab) in HSW1128
2/11/13 James Warne Targeted estrogen delivery reverses the metabolic syndrome
1/14/13 Megan Robblee Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance
1/7/13 Christophe Paillart Ablation of Sim1 neurons causes obesity through hyperphagia and reduced energy expenditure
12/17/12 MetaboRIPS MetaboRIPS: Catie Gleason (Pearce) and Atabai Lab
12/10/12 Suneil Koliwad Polysome Profiling in Liver Identifies Dynamic Regulation of Endoplasmic Reticulum Translatome by Obesity and Fasting
11/26/12 MetaboRIPS MetaboRIPS: James Warne (Xu) and Jonas Sjolund (Balmain)
11/19/12 Haruya Ono PTEN Loss in the Myf5 Lineage Redistributes Body Fat and Reveals Subsets of White Adipocytes that Arise from Myf5 Precursors
11/5/12 Jamila Newton Neuropeptide Transmission in Brain Circuits
10/29/12 MetaboRIPS MetaboRIPS: Louise Olofsson (Xu) and JP Upton (Oakes) in N-225
10/22/12 Stephanie Van Veen The Number of X Chromosomes Causes Sex Differences in Adiposity in Mice
10/15/12 Jess Porter Abate Antibiotics in early life alter the murine colonic microbiome and adiposity
10/1/12 Linet Mera Protein Modularity, Cooperative Binding, and Hybrid Regulatory States Underlie Transcriptional Network Diversification
9/24/12 Ivan Rudenko IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes
09/17/12 MetaboRIPS Metabolism Research in Progress Series: Yong Pan (Verdin Lab)
9/10/12 Kosaku Shinoda Temporal coding of insulin action through multiplexing of the AKT pathway
8/27/12 James Warne Leptin action through hypothalamic nitric oxide synthase-1–expressing neurons controls energy balance
8/20/12 Shi-Bing Yang Deconstruction of a neural circuit for hunger
8/13/12 Martin Valdearcos Contreras Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet.
8/6/12 Christophe Paillart Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery
7/23/12 Shingo Kajimura Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes
7/16/12 Megan Robblee Hyperresponsivity to Low-Dose Endotoxin during Progression to Nonalcoholic Steatohepatitis Is Regulated by Leptin-Mediated Signaling
7/9/12 Daniele Rottkamp Enteric glia are multipotent in culture but primarily form glia in the adult rodent gut
7/2/12 Louis Sharp A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
6/25/12 Yi Wang FoxO1 Target Gpr17 Activates AgRP Neurons to Regulate Food Intake
6/18/12 Ernie Yulyaningsih Involvement of Doublecortin-Expressing Cells in the Arcuate Nucleus in Body Weight Regulation
6/04/12 Sofie Nielsen Hypothalamic Neuropeptide Y (NPY) Controls Hepatic VLDL-Triglyceride Secretion in Rats via the Sympathetic Nervous System
05/14/12 Ivan Rudenko Fasting Activation of AgRP Neurons Requires NMDA Receptors and Involves Spinogenesis and Increased Excitatory Tone
05/07/12 Jillian Varonin IRS2 Signaling in LepR-b Neurons Suppresses FoxO1 to Control Energy Balance Independently of Leptin Action
04/30/12 Kosaku Shinoda Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity
04/23/12 James Warne Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity
04/16/12 Shi-Bing Yang Regulation of GABA and Glutamate Release from Proopiomelanocortin Neuron Terminals in Intact Hypothalamic Networks
04/02/12 Jamila Newton Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche
03/19/12 Daniele Rottkamp Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice
03/05/12 Shingo Kajimura Fibroblast Growth Factor-21 Regulates PPARγ Activity and the Antidiabetic Actions of Thiazolidinediones
02/27/12 Megan Robblee Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
02/13/12 Sofie Nielsen Distinct Roles for Specific Leptin Receptor Signals in the Development of Hypothalamic Feeding Circuits
02/06/12 Martin Contreras Autophagy in Hypothalamic AgRP Neurons Regulates Food Intake and Energy Balance
01/23/12 Clement Cheung Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice
01/16/12 No Meeting MLK day
01/09/12 Suneil Koliwad Obesity is associated with hypothalamic injury in rodents and humans
12/19/11 Yi Wang NPY and MC4R Signaling Regulate Thyroid Hormone Levels during Fasting through Both Central and Peripheral Pathways
12/12/11 Haruya Ono Adipocyte NCoR Knockout Decreases PPARγ Phosphorylation and Enhances PPARγ Activity and Insulin Sensitivity
12/05/11 Ivan Rudenko Transplanted Hypothalamic Neurons Restore Leptin Signaling and Ameliorate Obesity in db/db Mice
11/28/11 Kosaku Shinoda Dynamics of human adipose lipid turnover in health and metabolic diseases
11/21/11 Jamila Newton SfN review

11/14/11

Jess Porter Abate Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis
11/07/11 Allison Xu Neuropeptide Y and Agouti-Related Peptide Mediate Complementary Functions of Hyperphagia and Reduced Energy Expenditure in Leptin Receptor Deficiency
10/31/11 Stephanie Van Veen Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction
10/24/11 No Meeting Diabetes Center Retreat
10/17/11 James Warne Nicotine Decreases Food Intake Through Activation of POMC Neurons
10/03/11 Shi-Bing Yang Hunger States Switch a Flip-Flop Memory Circuit via a Synaptic AMPK-Dependent Positive Feedback Loop
10/10/11 No Meeting Columbus Day
09/26/11 Louise Olofsson Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity
09/19/11 Christophe Paillart Leptin Action via Neurotensin Neurons Controls Orexin, the Mesolimbic Dopamine System and Energy Balance
09/12/11 Suneil Koliwad An ADIOL-ERβ-CtBP Transrepression Pathway Negatively Regulates Microglia-Mediated Inflammation
09/05/11 No Meeting Labor Day
08/29/11 Haruya Ono Desnutrin/ATGL Is Regulated by AMPK and Is Required for a Brown Adipose Phenotype Rats
08/22/11 Yi Wang Moderate Long-Term Modulation of Neuropeptide Y in Hypothalamic Arcuate Nucleus Induces Energy Balance Alterations in Adult Rats
08/15/11 Shingo Kajimura Protection from Obesity and Diabetes by Blockade of TGF-β/Smad3 Signaling
08/01/11 Ivan Rudenko Proliferative Hypothalamic Neurospheres Express NPY, AGRP, POMC, CART and Orexin-A and Differentiate to Functional Neurons
07/18/11 Allison Xu Knockdown of NPY Expression in the Dorsomedial Hypothalamus Promotes Development of Brown Adipocytes and Prevents Diet-Induced Obesity
07/11/11 Shi-Bing Yang High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons
06/27/11 Jamila Newton Endo Conference review
06/20/11 James Warne Endo Conference review
06/13/11 Andrew Pierce Concepts and Controversies in Scaling Metabolic Rate: What Can We Do?
05/23/11 Christophe Paillart Role of Hypothalamic Melanocortin System in Adaptation of Food Intake to Food Protein Increase in Mice
05/16/11 Louise Olofsson Rapid, reversible activation of AgRP neurons drives feeding behavior in mice
05/09/11 Clement Cheung Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice
05/02/11 Ivan Rudenko Differential Distribution of Tight Junction Proteins Suggests a Role for Tanycytes in Blood-Hypothalamus Barrier Regulation in the Adult Mouse Brain
04/18/11 MeeJ Kim Role of Ucp1 enhancer methylation and chromatin remodelling in the control of Ucp1 expression in murine adipose tissue
04/11/11 Andrew Pierce Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2
04/04/11 Jamila Newton Early-Life Exposure to Testosterone Programs the Hypothalamic Melanocortin System
03/28/11 Nadav Ahituv Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3
03/21/11 Christophe Paillart Simultaneous POMC gene transfer to hypothalamus and brainstem increases physical activity, lipolysis and reduces adult-onset obesity.
03/07/11 James Warne Brain insulin controls adipose tissue lipolysis and lipogenesis
02/07/11 Shi-Bing Yang AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training
01/31/11 Clement Cheung Activation of Central, But Not Peripheral, Estrogen Receptors Is Necessary for Estradiol’s Anorexigenic Effect in Ovariectomized Rats & Intrauterine Position Affects Estrogen Receptor {alpha} Expression in the Ventromedial Nucleus of the Hypothalamus via Promoter DNA Methylation

01/24/11 Louise Olofsson Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity
01/10/11 Andrew Pierce CRTC3 links catecholamine signalling to energy balance
12/13/10 Jamila Newton Neuroscience meeting review
12/06/10 Shi-Bing Yang Leptin Rapidly Improves Glucose Homeostasis in Obese Mice by Increasing Hypothalamic Insulin Sensitivity
11/29/10 Nadav Ahituv Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity
11/08/10 Christophe Paillart Lack of leptin activity in blood samples of Adélie penguin and bar-tailed godwit
11/01/10 MeeJ Kim Postnatal Sim1 Deficiency Causes Hyperphagic Obesity and Reduced Mc4r and Oxytocin Expression
10/25/10 Louise Olofsson Disruption of hypothalamic leptin signaling in mice leads to early-onset obesity, but physiological adaptations in mature animals stabilize adiposity levels
10/18/10 Ivan Rudenko SIRT1 Deacetylase in POMC Neurons Is Required for Homeostatic Defenses against Diet-Induced Obesity
10/11/10 Melissa Meucci Rai1 haploinsufficiency causes reduced Bdnf expression resulting in hyperphagia, obesity and altered fat distribution in mice and humans with no evidence of metabolic syndrome.
10/04/10 James Warne Interleukin-6 signaling in liver-parenchymal cells suppresses hepatic inflammation and improves systemic insulin action
09/27/10 Clement Cheung Hypothalamic AMPK and fatty acid metabolism mediate
thyroid regulation of energy balance
09/20/10 Hélène Favre A sensitive period for environmental regulation of eating behavior and leptin sensitivity
09/13/10 Jamila Newton Agrp Neurons Mediate Sirt1's Action on the Melanocortin System and Energy Balance: Roles for Sirt1 in Neuronal Firing and Synaptic Plasticity
08/16/10 Allison Xu Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity

08/09/10

Louise Olofsson Kisspeptin Directly Excites Anorexigenic Proopiomelanocortin Neurons but Inhibits Orexigenic Neuropeptide Y Cells by an Indirect Synaptic Mechanism
08/02/10 Andrew Pierce Hyperleptinemia Is Required for the Development of Leptin Resistance
07/26/10 James Warne Melanocortin signaling in the CNS directly regulates circulating cholesterol
07/19/10 Ivan Rudenko Neurogenesis in the ependymal layer of the adult rat 3rd ventricle
07/12/10 Ritu Malhotra Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes
06/21/10 Melissa Meucci Signaling through Tyr985 of Leptin Receptor as an Age/Diet-Dependent Switch in the Regulation of Energy Balance
06/14/10 Shi-Bing Yang Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats
06/07/10 Hélène Favre Thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor expression
05/24/10 Clement Cheung Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits
05/17/10 Christophe Paillart Cholecystokinin Knockout Mice Are Resistant to High-Fat Diet-Induced Obesity
05/03/10 Jen Wade The Action of Leptin on Appetite-Regulating Cells in the Ovine Hypothalamus: Demonstration of Direct Action in the Absence of the Arcuate Nucleus
04/19/10 Jamila Newton Segregation of Acute Leptin and Insulin Effects in Distinct
Populations of Arcuate Proopiomelanocortin Neurons
04/12/10 Louise Olofsson Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically
04/05/10 Ivy Aslan Leptin therapy in insulin-deficient type I diabetes
03/29/10 Andrew Pierce Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis
03/22/10 James Warne Divergent Regulation of Energy Expenditure and Hepatic Glucose Production by Insulin Receptor in Agouti-Related Protein and POMC Neurons
03/15/10 Ivan Rudenko PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice
03/08/10 Inma Valle Asencio Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1
03/01/10 Hélène Favre Critical Role of Arcuate Y4 Receptors and the Melanocortin System in Pancreatic Polypeptide-Induced Reduction in Food Intake in Mice
02/22/10 Melissa Meucci Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats
02/08/10 Shi-Bing Yang Synchronized Network Oscillations in Rat Tuberoinfundibular Dopamine Neurons: Switch to Tonic Discharge by Thyrotropin-Releasing Hormone
02/01/10 Ritu Malhotra Autophagy regulates adipose mass and differentiation in mice
01/11/10 Jamila Newton Trophic effects of leptin
01/04/10 Clement Cheung Regulation of adaptive behaviour during fasting by hypothalamic Foxa2 + supplement
12/14/09 Louise Olofsson The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake & supplement
11/30/09 Andrew Pierce Molecular therapy of obesity and diabetes by a physiological autoregulatory approach
11/23/09 Ivan Rudenko Proopiomelanocortin Expression in both GABA and Glutamate Neurons
11/16/09 James Warne Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons + supplemental data
11/02/09 Ivy Aslan Modulation of Blood Pressure by Central Melanocortinergic Pathways
10/26/09 Jacqueline Siljee Adult Type 3 Adenylyl Cyclase­Deficient Mice Are Obese
10/19/09 Jen Wade Palmitic acid mediates hypothalamic insulin resistance by altering PKC-θ subcellular localization in rodents
10/05/09 Inma Valle Asencio Neuronal Protein Tyrosine Phosphatase 1B Deficiency Results in Inhibition of Hypothalamic AMPK and Isoform-Specific Activation of AMPK in Peripheral Tissues
09/21/09 Hélène Favre Inactivation of the Fto gene protects from obesity
09/14/09 Melissa Meucci FoxO1 inhibits leptin regulation of pro-opiomelanocortin promoter activity by blocking STAT3 interaction with specificity protein 1
08/31/09 Baran Ersoy White Adipose Tissue Cells Are Recruited by Experimental Tumors and Promote Cancer Progression in Mouse Models
08/24/09 Louise Olofsson Loss of GABAergic Signaling by AgRP Neurons to the Parabrachial Nucleus Leads to Starvation
08/17/09 Clement Cheung Leptin Acts via Leptin Receptor-Expressing Lateral Hypothalamic Neurons to Modulate the Mesolimbic Dopamine System and Suppress Feeding
08/10/09 Shi-Bing Yang

Cold-activated Brown Adipose Tissue in Healthy Men

Identification and Importance of Brown Adipose Tissue in Adult Humans

08/03/09 Andrew Pierce High-Fat Diet Induces Apoptosis of Hypothalamic Neurons
07/27/09 Allison Xu Regulation of Pancreatic β Cell Mass by Neuronal Signals from the Liver
07/20/09 Ivan Rudenko Leptin-Dependent Control of Glucose Balance and Locomotor Activity by POMC Neurons
07/13/09 Jamila Newton Endo meeting review
06/22/09 James Warne ADA meeting review
06/15/09 Jacqueline Siljee Central Nervous System Imprinting of the G Protein Gsα and Its Role in Metabolic Regulation
06/01/09 Jamila Newton 5-HT inhibition of rat insulin 2 promoter Cre recombinase transgene and proopiomelanocortin neuron excitability in the mouse arcuate nucleus
05/18/09 James Warne Leptin Targets in the Mouse Brain
05/11/09 Christian Vaisse Hindbrain Leptin Stimulation Induces Anorexia and Hyperthermia Mediated by Hindbrain Melanocortin Receptors
05/04/09 Hélène Favre Loss of Hypothalamic Response to Leptin During Pregnancy Associated with Development of Melanocortin Resistance
04/27/09 Melissa Meucci MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family
04/20/09 Woo-ping Ge Obesity induces functional astrocytic leptin receptors in hypothalamus
04/13/09 Florence Lee Neuromedin B and Gastrin-Releasing Peptide Excite Arcuate Nucleus Neuropeptide Y Neurons in a Novel Transgenic Mouse Expressing Strong Renilla Green Fluorescent Protein in NPY Neurons
04/06/09 Inma Valle Asencio Differential Responses of Orexigenic Neuropeptides to Fasting in Offspring of Obese Mothers
03/23/09 Ivy Aslan Intestinal Gluconeogenesis Is a Key Factor for Early Metabolic Changes after Gastric Bypass but Not after Gastric Lap-Band in Mice
03/03/09 Shi-Bing Yang A Mathematical Model of Murine Metabolic Regulation by Leptin: Energy Balance and Defense of a Stable Body Weight
02/23/09 Baran Ersoy Requirement of Bardet-Biedl Syndrome Proteins for Leptin Receptor Signaling
02/09/09 Andrew Pierce Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance + supplement
02/02/09 Jacqueline Siljee Keystone meeting review
01/26/09 Clement Cheung Maternal High-Fat Diet and Fetal Programming: Increased Proliferation of Hypothalamic Peptide-Producing Neurons That Increase Risk for Overeating and Obesity
01/12/09 Jen Wade Regulation of Feeding and Metabolism by Neuronal and Peripheral Clocks in Drosophila + Supplement
01/05/09 Jamila Newton Evidence for defective mesolimbic dopamine exocytosis in obesity-prone rats
12/15/08 James Warne PDK1 Deficiency in POMC-Expressing Cells Reveals FOXO1-Dependent and -Independent Pathways in Control of Energy Homeostasis and Stress Response
12/08/08 Liz Unger A Stress Signaling Pathway in Adipose Tissue Regulates Hepatic Insulin Resistance + Supplement
12/01/08 Andrew Pierce Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals
11/24/08 Jacqueline Siljee b-Arrestin–Mediated Localization of Smoothened to the Primary Cilium + Supplemental data
11/17/08 Louise Olofsson Ablation of estrogen receptor alpha (ERα) prevents upregulation of POMC by leptin and insulin
10/27/08 Sandy Do Overexpression of CART in the PVN Increases Food Intake and Weight Gain in Rats
11/03/08 Melissa Meucci Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance
10/20/08 Hélène Favre Evidence for Constitutive Neural Cell Proliferation in the Adult Murine Hypothalamus
10/13/08 Woo-Ping Ge A FLEX Switch Targets Channelrhodopsin-2 to Multiple Cell Types for Imaging and Long-Range Circuit Mapping
10/06/08 Allison Xu Hypothalamic IKKb/NF-kB and ER Stress Link Overnutrition to Energy Imbalance and Obesity + Supplemental
09/29/08 Inma Valle Asencio Brain-specific carnitine palmitoyl-transferase-1c: role in CNS fatty acid metabolism, food intake, and body weight
09/22/08 Shi-Bing Yang UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
09/15/08 Florence Lee Selective inactivation of Socs3 in SF1 neurons improves glucose homeostasis without affecting body weight
09/08/08 Baran Ersoy New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure + Supplement
08/25/08 Jamila Newton Imaging structure and function in the CNS (Cold Spring Harbor)
08/18/08 Sayali Ranadive Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span
08/11/08 Jen Wade Starvation after AgRP neuron ablation is independent of melanocortin signaling
08/04/08 Chrisitan Vaisse Leptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli
07/28/08 James Warne Upper intestinal lipids trigger a gut-brain-liver axis to regulate glucose production + Supplementary Information
07/21/08 Liz Unger Regulation of AgRP mRNA transcription and peptide secretion by acute and chronic inflammation
07/14/08 Louise Olofsson Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanisms
07/07/08 Clement Cheung Agouti-Related Peptide and MC3/4 Receptor Agonists Both Inhibit Excitatory Hypothalamic Ventromedial Nucleus Neurons
06/30/08 Andrew Pierce Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome
06/23/08 Various presenters ADA / Endo meeting summaries
05/19/08 Inma Valle Asencio TrkB Agonists Ameliorate Obesity and Associated Metabolic Conditions in Mice
05/12/08 Sandy Do Oxytocin deficiency mediates hyperphagic obesity of Sim1 haploinsufficient mice
05/05/08 Florence Lee Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice
04/29/08 Melissa Meucci Leptin promotes adult hippocampal neurogenesis in vivo and in vitro
04/22/08 Baran Ersoy Activation of Stat3 Signaling in AgRP Neurons Promotes Locomotor Activity
Stat3 is required in hypothalamic Agrp/Npy neurons for normal energy homeostasis
04/15/08 Jacqueline Siljee Bardet–Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia
Identification of Ciliary Localization Sequences within the Third Intracellular Loop of G Protein-Coupled Receptors
04/08/08 Jamila Newton Serotonin 5-HT2C Receptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors
04/01/08 Andrew Pierce Obesity and Hypertriglyceridemia Produce Cognitive Impairment
03/25/08 Allison Xu Disruption of leptin receptor expression in the pancreas directly affects β cell growth and function in mice
03/17/08 Ali Reed PYY modulation of cortical and hypothalamic brain areas predicts feeding behaviour in humans + Supplementary information + Background materials
03/11/08 Christian Vaisse Disruption of the RIIβ subunit of PKA reverses the obesity syndrome of agouti lethal yellow mice
03/04/08 Jen Wade The Acyclic CB1R Inverse Agonist Taranabant Mediates Weight Loss by Increasing Energy Expenditure and Decreasing Caloric Intake
Background material: Endocannabinoids and related N-acylethanolamines in the control of appetite and energy metabolism: emergence of new molecular players
02/28/08 Christian Vaisse, Allison Xu et al. Keystone meeting review
02/13/08 James Warne Enhanced Leptin-Stimulated Pi3k Activation in the CNS Promotes White Adipose Tissue Transdifferentiation + Supplemental Data
02/05/08 Liz Unger The central melanocortin system directly controls peripheral lipid metabolism + Supplimentary Material
01/29/08 Inma Valle Asencio Targeted Deletion of AIF Decreases Mitochondrial Oxidative Phosphorylation and Protects from Obesity and Diabetes
01/14/08 Sandy Do Tumor-induced anorexia and weight loss are mediated by the TGF- beta superfamily cytokine MIC-1
01/07/08 Melissa Meucci Developmental Switch in Neuropeptide Y and Melanocortin Effects in the Paraventricular Nucleus of the Hypothalamus
12/11/07 Baran Ersoy Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity
12/17/07 Jacqueline Siljee Melanocortin-4 Receptor Activation Stimulates Hypothalamic Brain-Derived Neurotrophic Factor Release to Regulate Food Intake, Body Temperature and Cardiovascular Function
11/19/07 Jamila Newton SfN meeting review - Topics on neuroscience imaging
11/13/07 Andrew Pierce SfN meeting review - Topics on neuroendocrine regulation of energy balance
10/29/07 Jamila Newton Endocrine Regulation of Energy Metabolism by the Skeleton
10/01/07 Christian Vaisse Disruption of Intraflagellar Transport in Adult Mice Leads to Obesity and Slow-Onset Cystic Kidney Disease + supplemental data
09/17/07 Sayali Ranadive Hyperphagia and Early Onset Obesity due to a Novel Homozygous Missense Mutation in Prohormone Convertase 1/3
08/27/07 Jennifer Wade Creation of a genetic model of obesity in a teleost
08/13/07 Andrew Pierce TLR4 links innate immunity and fatty acid-induced insulin resistance
07/23/07 Ali Reed Role of hepatic STAT3 in brain-insulin action on hepatic glucose production
07/09/07 Allison Xu Insulin Action in AgRP-Expressing Neurons Is Required for Suppression of Hepatic Glucose Production
06/25/07 Inma Valle Asencio Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
06/11/07 Liz Unger Hypothalamic resistin induces hepatic insulin resistance
05/29/07 Baran Ersoy Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small molecule hypophagic agents
05/07/07 Gabe Loeb A Key Role of Leptin in the Control of Regulatory T Cell Proliferation
03/19/07 Jacqueline Siljee A Central Thermogenic-like Mechanism in Feeding Regulation: An Interplay between Arcuate Nucleus T3 and UCP2
03/26/07 Melissa Meucci Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals
02/12/07 Andrew Pierce Altered Expression of SOCS3 in the Hypothalamic Arcuate Nucleus during Seasonal Body Mass Changes in the Field Vole, Microtus agrestis
01/22/07 Sayali Ranadive Role of the Central Melanocortin Circuitry in Adaptive Thermogenesis of Brown Adipose Tissue
01/08/07 Hélène Favre A brain-specific microRNA regulates dendritic spine development
12/11/06 Allison Xu Modulation of neuropeptide Y expression in adult mice does not affect feeding
10/30/06 Noelle Huskey miR-7b, a microRNA up-regulated in the hypothalamus after chronic hyperosmolar stimulation, inhibits Fos translation
09/24/06 Andrew Pierce Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells
08/28/06 Christian Vaisse Serotonin reciprocally regulates melanocortin neurons to modulate food intake
08/07/06 Baran Ersoy Vaccination against weight gain
07/24/06 Melissa Meucci Overfeeding in identical twins: 5-year postoverfeeding results
07/10/06 Simone Tchu Hypothalamic mTOR signaling regulates food intake
06/05/06 Gabe Loeb Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight
05/22/06 Hélène Favre Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake
05/08/06 Merisa Piper Reactive oxygen species have a causal role in multiple forms of insulin resistance
04/10/06 Noelle Huskey Divergent regulation of proopiomelanocortin neurons by leptin in the nucleus of the solitary tract and in the arcuate hypothalamic nucleus
03/27/06 Mehdi Skhiri Ghrelin controls hippocampal spine synapse density and memory performance

 

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